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7- and TLR9-dependent IFN-α induction, which is restricted to plasmacytoid dendritic cells. C protein interacts with a serine/threonine kinase IKKα and inhibits phosphorylation of IRF7. This anti-IFN activity of C protein is shared across genera of the Paramyxovirinae, and thus seems to play an important position in paramyxovirus immune evasion. It is suggested that poliomyelitis … Read more